For nausea and vomiting associated with pregnancy, first try changing your diet, says Jennifer Niebyl, M.D., University of Iowa professor and head of obstetrics and gynecology, in a report in the American Journal of Obstetrics and Gynecology. This includes frequent, small meals, a bedtime snack high in protein, and keeping crackers next to the bed for a first morning snack. If that doesn’t work, talk to your physician about Vitamin B6 and a medicine called doxylamine.